منابع مشابه
Hoxc13 mutant mice lack external hair.
Hox genes are usually expressed temporally and spatially in a colinear manner with respect to their positions in the Hox complex. Consistent with the expected pattern for a paralogous group 13 member, early embryonic Hoxc13 expression is found in the nails and tail. Hoxc13 is also expressed in vibrissae, in the filiform papillae of the tongue, and in hair follicles throughout the body; a patter...
متن کاملThe Biosynthesis of C13 Compounds
1. Starch, containing 7.05 atom per cent C(13) excess has been produced in the mesophyll cells of bean leaves, starting with C(13)O(2) containing 7.26 atom per cent C(13) excess. Approximately 67 per cent of the C(13) taken up by the leaves was determined in the starch fraction. 2. The soluble carbohydrate, containing 6.72 atom per cent C(13) excess, accounts for approximately 23 per cent of th...
متن کاملHomeobox Genes and the Homeobox
Most homeobox [5] genes [4] contain a 180-base-pair region called a homeodomain [6]. The homeodomain [6] portion of the protein transcript has been shown to interact with DNA in a cisregulatory fashion during the critical stages of early body plan specification and embryogenesis [7]. These sorts of interactions demonstrate the importance of regulatory genes [4] and their architectural role in t...
متن کاملHOX gene analysis in the osteogenic differentiation of human mesenchymal stem cells
Human bone marrow-derived mesenchymal stem cells (hMSCs) have the capacity to differentiate into osteoblasts during osteogenesis. Several studies attempted to identify osteogenesis-related genes in hMSCs. Although HOX genes are known to play a pivotal role in skeletogenesis, their function in the osteogenesis of hMSCs has not yet been investigated in detail. Our aim was to characterize the expr...
متن کاملHOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3
Esophageal squamous cell carcinoma (ESCC), the dominant subtype of esophageal cancer, is one of the most common digestive tumors worldwide. In this study, we confirmed that HOXC13, a member of the homeobox HOXC gene family, was significantly upregulated in ESCC and its overexpression was associated with poorer clinical characteristics and worse prognosis. Moreover, knockdown of HOXC13 inhibited...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/44752